Writing exercise
Make notes on anything that you think could be improved. Give yourself enough time to do this properly – perhaps ten minutes or so.
Date: Fri, 18 Sep 2022 12:28:15
To: Leonard.McCoy@nhs.net
Subject:
Dear Dr McCoy,
A large number of medicines interact with alcohol to cause drowsiness. However, alcohol is metabolised via alcohol dehydrogenase, cytochrome p450 and catalase and prescribed medicines are not known to induce or inhibit the activity of alcohol dehydrogenase or catalase. However, many prescribed medicines are metabolised with the cytochrome p450 enzyme system and some of them can induce or inhibit the enzymesʼ activity but interaction between medicines and alcohol via cytochrome p450 is unlikley. However, the route of metabolism for anotherine is not known and unlike a lot of centrally active drugs it does not appear to potentiate the affects of alcohol and this has even emboldenned the manufacturer to state in itʼs SmPC that ʻAnotherine does not appear to potentiate the effect of alcohol on cognitive functions in healthy volunteers.
Yours faithfully,
Anne
A. Newbie
Lord Ellpus NHS Foundation Trust
To: Leonard.McCoy@nhs.net
Subject:
Dear Dr McCoy,
A large number of medicines interact with alcohol to cause drowsiness. However, alcohol is metabolised via alcohol dehydrogenase, cytochrome p450 and catalase and prescribed medicines are not known to induce or inhibit the activity of alcohol dehydrogenase or catalase. However, many prescribed medicines are metabolised with the cytochrome p450 enzyme system and some of them can induce or inhibit the enzymesʼ activity but interaction between medicines and alcohol via cytochrome p450 is unlikley. However, the route of metabolism for anotherine is not known and unlike a lot of centrally active drugs it does not appear to potentiate the affects of alcohol and this has even emboldenned the manufacturer to state in itʼs SmPC that ʻAnotherine does not appear to potentiate the effect of alcohol on cognitive functions in healthy volunteers.
Yours faithfully,
Anne
A. Newbie
Lord Ellpus NHS Foundation Trust
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